1. Dr. HyeKyeung Seung
  2. CP-420-18
  3. (657)278-7175
  4. hseung@fullerton.edu

The Gluten-and Casein-Free Diet and Autism: Communication Outcomes From a Preliminary Double-Blind Clinical Trial

Abstract
This study retrospectively examined the efficacy of 8 gluten-free and case in-free (GFCF) diet intervention as a means to improve verbal/nonverbal communication in children withautismspectrumdisorders.Data were analyzed retrospectively from a randomized, double-blind, repeated measures cross over design study that included 13 children aged 2-16 years with autism spectrum disorders. Video recordings of at-home parent-child play were analyzed. Recordings were made at baseline, after 6 weeks on one of the diets (GFC For regular diet),and after 6 weeks on the alternate diet . Findings of the current study indicated no statistically significant differences in verbal and nonverbal communication outcomes between GFCF and regular diet conditions. While results of this study demonstrate that double-blind clinical trials of diet intervention are feasible, they are inconclusive regarding the efficacy of diet for improving communication. perhaps due to the relatively short period of diet intervention used. Directions for future research are discussed as well as Implications for clinical practice. Click Here to download the full article.


Intervention Outcomes of a Bilingual Child with Autism

Abstract
This longitudinal case study examined a child who was initially diagnosed with language delay at age 3 and subsequently diagnosed with autism at age 3 years 6 months. This case study is particularly interesting because it followed the child for 24 months and evaluated the efficacy of a unique Korean-English bilingual speech-language intervention. Speech-language intervention was provided twice weekly in his primary language, Korean, for the first 12 months by a Korean-English bilingual speech-language clinician. During the next 6 months, the intervention was gradually introduced in English; and by the final 6 months, the intervention was provided almost entirely in English. This study also incorporated information regarding parent interventions that was implemented by the parents at home. The child in this report made notable gains in expressive and receptive language development in both languages over the study period as well as decreases in aberrant behaviors. At the 24-month follow-up,he was able to respond to testing that was done completely in English. The results of this study support the practice of providing services in the primary language when English is not the language used at home to establish linguistic foundation of the primary language. As the child makes gains in the primary language, a gradual transition can be made to .intervention in English. Results of this study have important implications for future "research and clinical decision making for assisting families of children from a variety of cultural and ethnic backgrounds. Click Here to download the full article.


Approaches to Speech-Language Intervention and the True Believer

Abstract
Treatment approaches in speech-language therapy are sometimes selected and justified on the basis of a clinician's experience that "it works." Moreover, it has been argued (e.g., Kamhi, 1999) that such clinical judgment is, in principle, sound and should be endorsed. Contrary to this view, five extraneous effects are presented as confounding influences that invalidate clinical judgment as the sole basis for adopting a therapy approach. Clinicians should always question whether observed changes in their patients are due to their interventions or to extraneous effects. Possible controls for these effects are double- blind and single subject repeated measures. Research design suggestions are presented, with descriptions of the five extraneous effects. Click Here to download the full article.


Linguistic characteristics of individuals with high functioning autism and Asperger syndrome

Abstract
This study examined the linguistic characteristics of high functioning individuals with autism and Asperger syndrome. Each group consisted of 10 participants who were matched on sex, chronological age, and intelligence scores. Participants generated a narrative after watching a brief video segment of the Social Attribution Task video. Each participant was then asked 10 questions related to the stimulus video. The narrative samples and responses to the questions were analyzed linguistically. Individuals with high functioning autism and Asperger syndrome performed similarly on most measures of language function; however, results suggest there may be pragmatically-based differences between the groups in the use of verb tense markers. Click Here to download the full article.


Twin Language Development: A Case Study of a Twin with a Cochlear Implant and a Twin with Typical Hearing

Abstract
This study was a longitudinal examination (21 month follow-up) of language development in a pair of fraternal twins. One twin received a cochlear implant at age 20 months secondary to sensorineural hearing loss. The other twin had normal hearing. Data were obtained every 6 months following her initial cochlear implant stimulation. Both twins showed delayed expressive vocabulary skills at initial testing, but both demonstrated an expanding vocabulary over time. Receptive vocabulary of the twin with the cochlear implant at age 41 months was within the average range, but expressive vocabulary performance was delayed. When adjusted for length of implant use, expressive vocabulary performance was age appropriate. The twin with normal hearing progressed faster in expressive vocabulary development and performed within the average range by age 41 months. Click here to download the full article.


Verbal communication outcomes in children with autism after in-home father training

Abstract
Background This retrospective study examined the efficacy of in-home father training on the communicative outcomes of children with autism. The in home training consisted of two components: (I) expectant waiting; and (2) imitation with animation.
Methods Efficacy of parent training was examined by measuring the ratio of utterances produced by the parents to the utterances produced by the children and the number of verbal imitation by the parents. Outcomes of the children's verbal production were examined by measuring the number of (I) single word utterances; (2) different words produced; and (3) verbal response to questions.
Results Following training there was a decrease in the ratio of parent to child utterances and an increase in (I) the use of imitation by the parents; and (2) the number of single words and different words produced by the children.
Discussion Results of this study suggested that the parents had learned to wait for their children to communicate verbally during communicative interactions and to interact more efficiently with their children by using verbal imitation. Overall, the results of this study support the efficacy of parent training that focuses on promotion of social reciprocity, and have important implications for clinicians and future research.
Keywords autism, communication, communication outcome, father training, social reciprocity intervention
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Sentence memory of individuals with Down syndrome and typically developing children

Abstract
Background Individuals with Down’s syndrome (DS) have an auditory short-term memory span disproportionately shorter than the non-verbal mental age (MA). This study evaluated the Baddeley model’s claim that verbal short-term memory deficits might arise from slower speaking rates (and thus less material rehearsed in a 2 s passive store) by using the sentence memory subtest of the Stanford-Binet. Previous work had shown digit span recall speaking rate to be comparable to the examiner’s slow rate (one syllable per second) for both DS and language matched participants.
Method Thirty individuals with DS were compared to two control groups [non-verbal MA-matched and mean length of utterance (MLU)-matched] on the sentence span and speaking rate for the longest verbatim recalled sentence. Sentence stimuli were presented at a normal speaking rate. Results The DS group had shorter sentence memory span than the MA-matched group and a faster, rather than slower, speaking rate (syllables per second) than the MLU-matched controls.
Conclusions Language production level accounted for a substantial portion of the variance in the sentence memory span in the DS group. Thus, language production skill, rather than speaking rate, predicts variability in verbal memory span. Keywords Down’s syndrome, language production deficit, phonological loop, sentence memory, speaking rate, working memory. Click here to download the full article.


The effect of story presentation rates on story retelling by individuals with Down syndrome

Abstract
The current study examined the effect of story presentation rates on story recall performance in 35 individuals with Down syndrome and 3 control groups (35 mental age matched, 35 syntax comprehension matched, and 35 syntax production matched children). Three short audiotaped stories were presented to each individual at three different rates (normal, storyteller [slow with expressive inflections], and slow rate). The effect of group but not rate was significant. Individuals with Down syndrome recalled more content words than the production-matched group and the production matched group recalled fewer content words than the mental age matched and comprehension matched groups. The results were interpreted in relation to working memory deficits in individuals with Down syndrome, developmental change in story recall of typically developing children, and the contribution of syntax comprehension to story recall. Click here to download the full article.


Digit Span in Individuals With Down Syndrome and in Typically Developing Children: Temporal Aspects

Abstract
This study explored factors influencing digit span performance in individuals with Down syndrome. The following questions were asked: Is there a deficit in the phonological loop, either in articulatory rehearsal (measured in speaking rate and recall latency) or in the passive store (measured in recall duration)? Is reduced auditory short-term memory associated with a language production deficit? Thirty five adolescents with trisomy 21 Down syndrome were compared to 35 mental-age-matched and 35 language-production-matched controls. There was no group difference in speaking rate. The DS group had shorter digit spans than the MA controls. Language production level accounted for substantial variance in digit span in individuals with Down syndrome.
KEY WORDS: Down syndrome, digit span, working memory, phonological loop, language production deficit
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Predicting Language Production in Children and Adolescents With Down Syndrome: The Role of Comprehension

Abstract
Predictors of language production skills in 12-minute narratives are investigated cross-sectionally in 48 children and adolescents with Down syndrome (trisomy 21), aged 5 to 20 years, in comparison to 48 control children aged 2 to 6 years matched statistically for nonverbal mental age and mother’s years of education. Two models were evaluated by hierarchical regression analyses using predictors drawn from the domains of group membership, chronological age, cognition, socioeconomic status, and hearing screening status (Model I) and, additionally, comprehension performance (Model II). Results showed that Model II was more successful. In the DS group, it explained 68% of the variability in number of different words, 80% in MLU, and 32% in intelligibility. Corresponding percentages for the control group were 72%, 71%, and 26%. A mechanism linking comprehension of input to early stages of production practice through activation of the early speech motor area is proposed.
KEY WORDS: Down syndrome, mental retardation, language
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